Porcine pleuropneumonia (PPN; currently referred to as APP) is widely distributed throughout major swine-raising countries. It has been a major problem in many European countries and is relatively common in the United States, Canada and Asia. APP is restricted to swine. In naïve herds, APP occurs in all age groups but usually is seen in 6-20 week old pigs. Actinobacillus suis can cause similar disease and lesions but is not as contagious as Actinobacillus pleuropneumoniae (APP).

The Kernel APP kit is an indirect ELISA kit for the detection of antibodies against APP serotypes 1 through 12 in swine serum, plasma and meat juice.